|
Colestipol Side Effects |
||||||||||||||
|
Colestipol Review Questions and Answers
|
||||||||||||||
|
Trade Name: Colestipol Generic Names: Colestid What is the indication for Colestipol? Colestipol is indicated for treatment hypercholesterolemia What is the mechanism of Colestipol? Colestipol is an ion exchange resin that binds to bile acids removing bile acids from the enterohepatic circulation, leading to increased oxidation of cholesterol to bile acids. therefore decreasing the cholesterol levels Is Colestipol safe in pregnancy? Colestipol has been given a pregnancy category B. . This means that this drug is presumed safe in pregnancy, based on animal studies Is Colestipol found in breast milk? Colestipol is not found in breast milk, but it may interfere with proper vitamin absorption and alter the breast milk How is Colestipol metabolized? Colestipol is minimally absorbed from the gastrointestinal tract
Adverse events in people treated with Colestipol
|
||||||||||||||
Pharmacology
Question:
What is the mechanism of
colestipol?
Answer:
Colestipol binds to bile acids in the intestine leading to increased excretion
of bile acid in the feces leading to increased oxidation of cholesterol to bile
acids resulting in increased numbers of low density lipoprotein receptors with
increased hepatic uptake of LDL and lower serum cholesterol levels
Question:
What is the most common side
effect of colestipol?
Answer:
The most common side effect of
colestipol is constipation
Question:
How could colestipol
result in increased bleeding tendencies?
Answer:
Colestipol can lead to
vitamin K deficiency