Doxazosin Side Effects

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Doxazosin Review Questions and Answers

Trade Name:  Cardura side effects
Generic Names:  Doxazosin Side Affects
Adverse events seen in patients treated with doxazosin for hypertension
Gastrointestinal Nausea 3%
Diarrhea 2%
Constipation 1%
Dyspepsia 1%
Flatulence 1%
Neurological Headache 14%
Paresthesia 1%
Kinetic Disorders 1%
Ataxia 1%
Hypertonia 1%
Muscle Cramps 1%
Cardiovascular Dizziness 19%
Vertigo 2%
Postural Hypotension 0.3%
Edema 4%
Palpitation 2%
Arrhythmia 1%
Hypotension 1%
Tachycardia 0.3%
Peripheral Ischemia 03%
Genitourinary Polyuria 2% 0%
Urinary Incontinence 1%
Musculoskeletal Arthralgia/Arthritis 1%
Muscle Weakness 1%
Myalgia 1%
General Mouth Dry 2%
Flushing 1%
Vision Abnormal 2%
Conjunctivitis/Eye Pain 1%
Tinnitus 1%
Fatigue/Malaise 12%
Chest Pain 2%
Asthenia 1%
Face Edema 1%
Pain 2%
Psychiatric Somnolence 5%
Nervousness 2%
Depression 1%
Insomnia 1%
Sexual Dysfunction 2%
Dermatologic Rash 1%
Pruritus 1%
Respiratory Rhinitis 3%
Dyspnea 1%
Epistaxis 1%
Doxazosin Pharmacology
Question:
What is the half-life of Doxazosin?
Answer:
The elimination half-life of Doxazosin is approximately 22 hours.
Question:
Is Doxazosin associated with the first dose syncope?
Answer:
Doxazosin can be associated with syncope occurring within 90 minutes of the first dose.
Question:
How is Doxazosin metabolized?
Answer:
Doxazosin is metabolized by the liver.
Question:
Why should garlic be avoided in patients taking Doxazosin?
Answer:
Garlic may increase the antihypertensive effect Doxazosin.