Side Effects of Heparin

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Heparin Review Questions and Answers

Trade Name:  What Are the Side Effects of Heparin?
What are the side effects for Heparin?
The primary side effect of heparin is bleeding. Heparin can also result in heparin induced thrombocytopenia.
What is the mechanism of Heparin?
Heparin binds to anti-thrombin III, and activates antithrombin III which in turn inactivates thrombin, factor X, factor IX, factor XI.
How is Heparin excreted?
 Heparin is metabolized by the reticuloendothelial system.
 Adverse events in people taking with Heparin
Gastrointestinal

Gastrointestinal bleeding

Neurological Hemorrhagic strokes
Cardiac ....
Genitourinary Hematuria
Pulmonary ....
Endocrine ....
Hematologic Thrombocytopenia, thrombosis
Pharmacology- Heparin
Question:
What is the action of unfractionated heparin, the half life, and how do you follow it?
Answer:
Action-activated antithrombin III
Half-life is 90 minutes
Follow with the PTT
Question:
What is the mechanism of heparin?
Answer:
Heparin catalyzes the activation of antithrombin III