Side Effects of Hydralazine

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Hydralazine Review Questions and Answers

Trade Name:  What are the side effects of Apresoline?
Generic Names:  What are the side effects of Hydralazine?
What are the side effects for Hydralazine?
The side effects of Hydralazine include flushing, headache, nausea, reflex tachycardia. Approximate 10 percent of people can develop a lupus like syndrome.
What is the mechanism of Hydralazine?
Hydralazine, results in arterial vasodilation by activating one guanylate cyclase leading to increased cGMP resulting in the phosphorylation of myosin and increased permeability to potassium.
How is Hydralazine excreted?
 Hydralazine is metabolized by the liver
 Adverse events in people taking with Hydralazine
Gastrointestinal Nausea
Neurological Headache
Cardiac Flushing, tachycardia
Genitourinary ...
Pulmonary ...
Rheumatologic Lupus like syndrome
Hematologic ...
Pharmacology - Hydralazine
Question:
How is hydralazine associated with SLE?
Answer:
Hydralazine has been associated with a syndrome consistent with lupus in a small percentage of patients.
Question:
How does Hydralazine affect the heart rate?
Answer:
Hydralazine is associated with an increase in the heart rate is not given concomitantly with another drug
such as a beta blocker.
Question:
What is the effect of Hydralazine?
Answer:
Hydralazine results in vasodilation of the arteries and arterioles.