Side Effects of Indomethacin

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Indomethacin Review Questions and Answers

Trade Name:  Indocin
Generic Names:  Indomethacin
Incidence of indomethacin side effects > 1%
Gastrointestinal Nausea
Dyspepsia
Diarrhea
Abdominal distress or pain
Constipation
Neurological Headache (11.7%)
Dizziness
Vertigo
Somnolence
Depression and fatigue
Tinnitus
Pharmacology of Indomethacin:
Question:
What is the strongest anti-inflammatory among the NSAIDS?
Answer:
Indomethacin is the strongest anti-inflammatory among the NSAIDS.
Question:
What is most frequent CNS side effect of indomethacin?
Answer:
The most frequent CNS side effect of indomethacin is a frontal headache which occurs in 25-50% of
patients who use this medication on a long-term basis.
Question:
How does indomethacin effect furosemide?
Answer:
Indomethacin can decrease the antihypertensive effects of furosemide.
Question:
How does indomethacin change the therapeutic benefit of ACE inhibitors?
Answer:
Indomethacin can decrease the antihypertensive effects of ACE inhibitors.