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Side Effects of Acyclovir (Zovirax) |
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Acyclovir Review Questions and Answers
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| Trade Name: Zovirax |
| Generic Names: Acyclovir |
| What are the Side effects of Acyclovir ? |
| Acyclovir is relatively safe to use with minimal side effects. At high doses the drug may form crystals in the urinary tract resulting in genitourinary dysfunction. |
| How is acyclovir excreted?? |
| Acyclovir is metabolized and renally excreted. |
| What is Mechanism of Acyclovir? |
| Acyclovir is an antiviral agent and is used to treat herpes simplex and herpes zoster infections. It can also sometimes be used to treat oral hairy leukoplakia in patients with EBV. Acyclovir is phosphorylated by viral thymidine kinase where it acts as a viral DNA polymerases inhibitor and a chain terminator. |
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Adverse events in people taking with Acyclovir |
| Gastrointestinal | .... |
| Neurological | .... |
| Musculoskeletal | .... |
| Genitourinary | Urine crystals |
| Dermatologic | .... |
| Psychiatric | ... |
| Neurologic | .... |
| Pharmacology - Acyclovir |
| Question: |
| What is the mechanism of Acyclovir? |
| Answer: |
| This drug inhibits viral DNA polymerases after phosphorylation by viral thymidine kinase |
| Question: |
| How does acyclovir work against HSV-I and HSV-II infections? |
| Answer: |
| Orally absorbed, it is Activated by HSV thymidine kinase Interferes with production of new viruses |