Symptoms of Mono

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Mono (Mononucleosis) symptoms occur in patients with infectious mononucleosis. The causative agent is the Epstein Barr virus (EBV). Approximately 90% of adults have had exposure to the EBV virus. It is spread by direct contact with secretions such as saliva.

The classic triad of mononucleosis symptoms include pharyngitis (sore throat), adenopathy (enlarged lymph nodes in the neck), and fever.


More than 90% of people will have fever. People will also often have chills, headache, muscle aches, joint aches, nausea, vomiting, abdominal pain, jaundice, and decreased appetite with weight loss.


Other mono symptoms include splenomegaly (enlarged spleen), particularly during the second week of illness. Rash sometimes occurs.

 
To view information about symptoms of Mononucleosis go to our Mononucleosis questions and answers page.
To view specific information about topics related to Mononucleosis symptoms go to our Topics page.
To view laboratory abnormalities go to our Labs page.
To view the side effects of medication associated with the treatment of Mononucleosis go to our Pharmacology page.
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To view the and differential diagnosis of Mononucleosis symptoms go to our Medicine Methods page.

Symptoms of Mononucleosis often do not lead directly to the underlying diagnosis and many symptoms can be misleading. Please review all concerns and information found on this website with your health care provider.